Spitzer J, Hennessy E, Neville L
Departmental of Environmental and Preventive Medicine, St Bartholomew's and the London School of Medicine and Dentistry, Queen Mary, University of London.
Br J Gen Pract. 2001 Feb;51(463):101-5.
General practitioners and the microbiologist serving north Hackney in north east London formed the impression, that of throat swabs sent to the laboratory, a disproportionate number of those positive for group A streptococcus appeared to come from Orthodox Jewish patients.
To confirm the clinical impression that the pharyngeal carriage of group A streptococci was higher in the Orthodox Jewish population than in other members of the population in the same locality.
A general practice questionnaire survey of all patients aged three years or over attending two practices that are about one kilometre apart, over a five-week period.
Two general practices in north London, one of which had a significant Orthodox Jewish patient list.
Throat swabs were taken from eligible patients who were invited to participate by completing a questionnaire and having a throat swab taken.
Swabs were taken from 1223 people. After correction for age (child or adult) and history of recent sore throat, the Orthodox Jewish community had a significantly higher carriage rate of group A streptococci than the rest of the population (odds ratio = 5.0 [2.1 to 11.9]). The proportion of adults with group A streptococci with and without sore throats was 6.4% and 2.4% respectively in the Orthodox Jewish group and 0.45% and 1% respectively in the 'others' group. The proportion of children with group A streptococci with and without sore throats was 17.4% and 5.9% respectively and 3.4% and 0% respectively in the others. These differences were not explained by the larger family size and domestic overcrowding in the Orthodox Jewish group.
Orthodox Jews in north London have a higher pharyngeal carriage rate of group A streptococci than the neighbouring population. These results may have implications for the diagnosis and treatment of acute sore throat in Orthodox Jewish patients, especially children.
在伦敦东北部哈克尼北部服务的全科医生和微生物学家形成一种印象，即送往实验室的咽喉拭子中，A 组链球菌呈阳性的样本中，来自东正教犹太患者的比例过高。
证实临床印象，即东正教犹太人群体中 A 组链球菌的咽部携带率高于同一地区的其他人群。
对所有三岁及以上患者进行全科问卷调查，这些患者来自相距约一公里的两家诊所，调查为期五周。
伦敦北部的两家全科诊所，其中一家有大量东正教犹太患者名单。
从符合条件的患者中采集咽喉拭子，这些患者通过填写问卷并接受咽喉拭子采集被邀请参与。
共采集了 1223 人的拭子。在校正年龄（儿童或成人）和近期咽痛病史后，东正教犹太社区 A 组链球菌的携带率显著高于其他人群（优势比 = 5.0 [2.1 至 11.9]）。在东正教犹太人群体中，有咽痛和无咽痛的成人 A 组链球菌比例分别为 6.4%和 2.4%，而在“其他”群体中分别为 0.45%和 1%。在有咽痛和无咽痛的儿童中，东正教犹太人群体中 A 组链球菌比例分别为 17.4%和 5.9%，而在其他群体中分别为 3.4%和 0%。这些差异无法用东正教犹太群体中较大的家庭规模和家庭拥挤来解释。
伦敦北部的东正教犹太人 A 组链球菌的咽部携带率高于邻近人群。这些结果可能对东正教犹太患者，尤其是儿童的急性咽痛诊断和治疗有影响。
