Benke G, Sim M, Fritschi L, Aldred G
Department of Epidemiology and Preventive Medicine, Monash University, Praham, Victoria, Australia.
Appl Occup Environ Hyg. 2001 Feb;16(2):149-53. doi: 10.1080/104732201460244.
A task exposure database (TED) was developed to facilitate data collation for construction of a task exposure matrix (TEM) for Healthwise, a series of studies on cancer and respiratory morbidity in the alumina and primary aluminium industry. Following the construction of job classifications for the eight study sites, the site hygienists identified all historical air monitoring time-weighted average (TWA) data, from their respective sites. The earliest data were sampled in the late 1970s, and over 17,000 personal samples were recorded over the eight sites over a twenty-year period. TED, a Microsoft Access database, was developed for use by site occupational hygienists to collate these exposure data across the mines, refineries and smelters. All data conforming to strict criteria for use were recorded using TED and provided to the study group. Following the individual data point entry, a calculator program in TED systematically calculated the geometric means, arithmetic means, and maximum and minimum results at the task level. Other features of TED included fields for flagging "significant changes" and "stepwise changes" in exposure. TED established a standardised means of data collation that later formed the basis for the construction of a TEM for the study. A TEM is similar to a job exposure matrix (JEM) except that the basic unit of categorization is at the task level instead of at the job level. Both a TEM and JEM have been constructed independently for Healthwise. The possible reduction of exposure misclassification and improvement in validity of exposure characterization with the use of the TEM, is currently under investigation. The Healthwise TEM consists of annual TWA and peak data results for each site for various airborne contaminants, including fluorides, coal tar pitch volatiles, sulfur dioxide, inspirable dust, alumina dust, bauxite dust, and oil mist. Construction of the TEM for the Healthwise study was completed in late 1998 and consists of over 33,700 TWA years of task exposure data.
为了便于整理数据,以便为“健康明智”项目构建任务暴露矩阵(TEM),开发了一个任务暴露数据库(TED)。“健康明智”项目是关于氧化铝和原铝行业癌症与呼吸道疾病的一系列研究。在为八个研究地点构建工作分类之后,各地点的卫生学家确定了各自地点所有的历史空气监测时间加权平均值(TWA)数据。最早的数据采样于20世纪70年代末,在二十年时间里,八个地点记录了超过17000份个人样本。TED是一个微软Access数据库,供各地点的职业卫生学家用于整理这些跨矿山、精炼厂和冶炼厂的暴露数据。所有符合严格使用标准的数据都通过TED记录并提供给研究小组。在输入各个数据点之后,TED中的一个计算器程序会系统地计算任务层面的几何平均值、算术平均值以及最大值和最小值结果。TED的其他功能还包括用于标记暴露中“显著变化”和“逐步变化”的字段。TED建立了一种标准化的数据整理方式,后来成为该研究构建任务暴露矩阵的基础。任务暴露矩阵与工作暴露矩阵(JEM)类似,只是分类的基本单位是任务层面而非工作层面。“健康明智”项目已分别构建了任务暴露矩阵和工作暴露矩阵。目前正在研究使用任务暴露矩阵是否可能减少暴露错误分类并提高暴露特征描述的有效性。“健康明智”项目的任务暴露矩阵包含各个地点针对各种空气传播污染物(包括氟化物、煤焦油沥青挥发物、二氧化硫、可吸入粉尘、氧化铝粉尘、铝土矿粉尘和油雾)的年度时间加权平均值和峰值数据结果。“健康明智”项目的任务暴露矩阵构建工作于1998年末完成,包含超过33700个任务暴露数据的时间加权平均值年份。