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对德克萨斯州博蒙特一家炼油厂熟练工匠接触空气中石棉的回顾性暴露评估(1940 - 2006年)。

Retrospective exposure assessment of airborne asbestos related to skilled craftsmen at a petroleum refinery in Beaumont, Texas (1940-2006).

作者信息

Williams Pamela, Paustenbach Dennis, Balzer J LeRoy, Mangold Carl

机构信息

ChemRisk Boulder, Colorado 80301, USA.

出版信息

J Toxicol Environ Health A. 2007 Jul;70(13):1076-107. doi: 10.1080/15287390701208305.

Abstract

Despite efforts over the past 50 or more years to estimate airborne dust or fiber concentrations for specific job tasks within different industries, there have been no known attempts to reconstruct historical asbestos exposures for the many types of trades employed in various nonmanufacturing settings. In this paper, 8-h time-weighted average (TWA) asbestos exposures were estimated for 12 different crafts from the 1940s to the present day at a large petroleum refinery in Beaumont, TX. The crafts evaluated were insulators, pipefitters, boilermakers, masons, welders, sheet-metal workers, millwrights, electricians, carpenters, painters, laborers, and maintenance workers. This analysis quantitatively accounts for (1) the historical use of asbestos-containing materials at the refinery, (2) the typical workday of the different crafts and specific opportunities for exposure to asbestos, (3) industrial hygiene asbestos air monitoring data collected at this refinery and similar facilities since the early 1970s, (4) published and unpublished data sets on task-specific dust or fiber concentrations encountered in various industrial settings since the late 1930s, and (5) the evolution of respirator use and other workplace practices that occurred as the hazards of asbestos became better understood over time. Due to limited air monitoring data for most crafts, 8-h TWA fiber concentrations were calculated only for insulators, while all other crafts were estimated to have experienced 8-h TWA fiber concentrations at some fraction of that experienced by insulators. A probabilistic (Monte Carlo) model was used to account for potential variability in the various data sets and the uncertainty in our knowledge of selected input parameters used to estimate exposure. Significant reliance was also placed on our collective professional experiences working in the fields of industrial hygiene, exposure assessment, and process engineering over the last 40 yr. Insulators at this refinery were estimated to have experienced 50th (and 95th) percentile 8-h TWA asbestos exposures (which incorporated 8-h TWA fiber concentrations, respirator use and effectiveness, and time spent working with asbestos-containing materials) of 9 (16) fibers/cc (cubic centimeter) from 1940 to 1950, 8 (13) fibers/cc from 1951 to 1965, 2 (5) fibers/cc from 1966 to 1971, 0.3 (0.5) fibers/cc from 1972 to 1975, and 0.005 (0.02) fibers/cc from 1976 to 1985 (estimated exposures were <0.001 fibers/cc after 1985). Estimated 8-h TWA exposures for all other crafts were at least 50- to 100-fold less than that of insulators, with the exception of laborers, whose estimated 8-h TWA exposures were approximately one-fifth to one-tenth of those of insulators. In spite of the data gaps, the available evidence indicates that our estimates of 8-h TWA asbestos exposures reasonably characterize the typical range of values for these categories of workers over time.

摘要

尽管在过去50多年里人们一直在努力估算不同行业特定工作任务中的空气粉尘或纤维浓度,但对于各种非制造环境中众多工种的历史石棉暴露情况,尚无已知的重建尝试。在本文中,我们估算了得克萨斯州博蒙特市一家大型炼油厂从20世纪40年代至今12种不同工种的8小时时间加权平均(TWA)石棉暴露量。所评估的工种包括绝缘工、管道工、锅炉工、泥瓦匠、焊工、钣金工、机械修理工、电工、木匠、油漆工、劳工和维修工人。该分析定量考虑了以下因素:(1)炼油厂含石棉材料的历史使用情况;(2)不同工种的典型工作日以及接触石棉的具体机会;(3)自20世纪70年代初以来在该炼油厂及类似设施收集的工业卫生石棉空气监测数据;(4)自20世纪30年代末以来已发表和未发表的关于各种工业环境中特定任务粉尘或纤维浓度的数据集;(5)随着时间推移人们对石棉危害的认识不断加深,呼吸器使用情况及其他工作场所做法的演变。由于大多数工种的空气监测数据有限,仅计算了绝缘工的8小时TWA纤维浓度,而所有其他工种的8小时TWA纤维浓度估计为绝缘工所经历浓度的一定比例。使用概率(蒙特卡洛)模型来考虑各种数据集中的潜在变异性以及用于估算暴露量的选定输入参数的知识不确定性。过去40年里我们在工业卫生、暴露评估和过程工程领域的集体专业经验也起到了重要作用。据估计,该炼油厂的绝缘工在1940年至1950年期间的第50百分位(和第95百分位)8小时TWA石棉暴露量(包括8小时TWA纤维浓度、呼吸器使用及有效性以及使用含石棉材料的工作时间)为9(16)纤维/立方厘米,1951年至1965年为8(13)纤维/立方厘米,1966年至1971年为2(5)纤维/立方厘米,1972年至1975年为0.3(0.5)纤维/立方厘米,1976年至1985年为0.005(0.02)纤维/立方厘米(1985年之后估计暴露量<0.001纤维/立方厘米)。除劳工外,所有其他工种的估计8小时TWA暴露量至少比绝缘工低50至100倍,劳工的估计8小时TWA暴露量约为绝缘工的五分之一至十分之一。尽管存在数据缺口,但现有证据表明,我们对8小时TWA石棉暴露量的估计合理地描述了这些工种工人随时间变化的典型值范围。

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