Kawano S, Tsuji S
Department of Clinical Laboratory Science, School of Allied Health Sciences, Faculty of Medicine Osaka University.
Nihon Rinsho. 2001 Feb;59(2):319-22.
In Japan, The new triple therapy was opened for Helicobacter pylori (HP) eradication from Nov. 1, 2000. The Japanese Society for Helicobacter Research presented a guideline for HP eradication. It recommended that HP infection should be checked at least 4 weeks after the treatment for peptic ulcer and HP infection using HPIgG antibody, rapid urease test, urea breath test, histology and/or culture. However, it did not state the best way and suitable timing to check HP infection after the eradication therapy. In this study, we investigated the accuracy of PyloriTek test(a 1-h rapid urease test) and tried to establish the suitable timing for checking HP infection after eradication therapy. In conclusion, when patients are examined more than 4 months after eradication therapy, the use of PyloriTek alone may be sufficient for correctly diagnosing HP infection.
在日本，新型三联疗法于2000年11月1日开始用于根除幽门螺杆菌（HP）。日本幽门螺杆菌研究学会提出了HP根除指南。该指南建议，对于消化性溃疡和HP感染患者，应在治疗后至少4周使用HP IgG抗体、快速尿素酶试验、尿素呼气试验、组织学和/或培养法检查HP感染情况。然而，该指南并未说明根除治疗后检查HP感染的最佳方法和合适时机。在本研究中，我们调查了PyloriTek试验（一种1小时快速尿素酶试验）的准确性，并试图确定根除治疗后检查HP感染的合适时机。总之，在根除治疗4个月后对患者进行检查时，单独使用PyloriTek可能足以正确诊断HP感染。
