Brunt E M
Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri, USA.
Clin Liver Dis. 2001 Feb;5(1):1-15, v. doi: 10.1016/s1089-3261(05)70151-3.
Benign tumors of the liver, less commonly encountered than metastatic or primary liver tumors, may present clinically with symptoms due to mass effect, or may be discovered incidentally during radiographic evaluation or surgical exploration for other clinical indications. Many of the lesions that result in a benign liver mass are true neoplasms, while others result from reactive proliferation of hepatocytes, biliary cells, mesenchymal or inflammatory cells. The premalignant nature or potential for malignant transformation is of concern in some of the benign tumors or tumor-like masses of the liver. In this article, benign tumors and tumor-like masses involving the adult liver are discussed with a focus on histopathology, histogenesis, and clinical significance of these interesting and unusual lesions.
肝脏良性肿瘤比转移性或原发性肝脏肿瘤少见,临床上可能因占位效应而出现症状,也可能在因其他临床指征进行影像学评估或手术探查时偶然发现。许多导致肝脏良性肿块的病变是真性肿瘤,而其他病变则是肝细胞、胆管细胞、间充质或炎症细胞反应性增生所致。肝脏的一些良性肿瘤或肿瘤样肿块的癌前性质或恶性转化潜能令人关注。在本文中,将讨论累及成人肝脏的良性肿瘤和肿瘤样肿块,重点关注这些有趣且不寻常病变的组织病理学、组织发生及临床意义。