Christensen V, Glenthøj B Y
H:S Bispebjerg Hospital, psykiatrisk afdeling E.
Ugeskr Laeger. 2001 Jan 15;163(3):301-2.
The malignant neuroleptica syndrome (MNS) and the serotonin syndrome (SS) can be impossible to differentiate. This case history describes clinical symptoms compatible with either MNS or SS in a 59-year-old schizophrenic male patient, who had been heavily medicated with antipsychotics for several years in close relation to initiation of new treatment with a SSRI compound. The case shows that it is important to have both syndromes in mind when chronically ill patients are treated with several medicaments.
恶性抗精神病药物综合征(MNS)和血清素综合征(SS)可能难以区分。本病例描述了一名59岁男性精神分裂症患者出现的与MNS或SS相符的临床症状,该患者在开始使用一种SSRI类化合物进行新治疗时,已连续数年大量服用抗精神病药物。该病例表明,在对慢性病患者使用多种药物进行治疗时,同时考虑这两种综合征很重要。