Ener Rasih Atilla, Meglathery Sharon B, Van Decker William A, Gallagher Rollin M
MCP Hahnemann University Hospitals, Philadelphia, Pennsylvania 19102, USA.
Pain Med. 2003 Mar;4(1):63-74. doi: 10.1046/j.1526-4637.2003.03005.x.
Serotonin syndrome is an iatrogenic disorder induced by pharmacologic treatment with serotonergic agents that increases serotonin activity. In addition, there is a wide variety of clinical disorders associated with serotonin excess. The frequent concurrent use of serotonergic and neuroleptic drugs and similarities between serotonin syndrome and neuroleptic malignant syndrome can present the clinician with a diagnostic challenge. In this article, we review the pathophysiology, diagnosis, and treatment of serotonin syndrome as well as other serotonergic disorders.
血清素综合征是一种医源性疾病，由使用增加血清素活性的血清素能药物进行药物治疗引起。此外，还有多种与血清素过量相关的临床疾病。血清素能药物和抗精神病药物的频繁联合使用以及血清素综合征与抗精神病药物恶性综合征之间的相似性，给临床医生带来了诊断挑战。在本文中，我们综述了血清素综合征以及其他血清素能疾病的病理生理学、诊断和治疗。
