Bosma J J, Kirollos R W, Broome J, Eldridge P R
Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, England.
Neurosurgery. 2001 Feb;48(2):420-3. doi: 10.1097/00006123-200102000-00038.
The exact origin of rare intradural chondrosarcomas remains obscure. We present a case report of an intradural classic chondrosarcoma (a very rare subtype of chondrosarcoma in this location), with a review of the literature, in an attempt to clarify the histogenesis of these tumors.
A 48-year-old man presented with a 12-month history of progressive right hemiparesis. Computed tomography and magnetic resonance imaging demonstrated a left parietal space-occupying lesion.
The patient underwent an image-guided, left parietal parasagittal craniotomy. An extrinsic tumor, which seemed to arise from the dura, was macroscopically removed. There was no bone involvement. The histological examination revealed a Grade II classic chondrosarcoma with tumor infiltration into the dura. Adjuvant radiotherapy was administered.
Intradural chondrosarcomas are rare tumors, the majority of which are mesenchymal. Classic chondrosarcomas in this location are much rarer. Their histogenesis is uncertain. In this case, the origin seems to be from the dura. Because of the malignant potential of these tumors, radical extirpation whenever possible, followed by radiotherapy, is indicated.
罕见的硬脊膜内软骨肉瘤的确切起源仍不清楚。我们报告一例硬脊膜内经典型软骨肉瘤（该部位软骨肉瘤的一种非常罕见的亚型）病例，并对文献进行综述，以试图阐明这些肿瘤的组织发生。
一名48岁男性，有12个月进行性右半身轻瘫病史。计算机断层扫描和磁共振成像显示左顶叶占位性病变。
患者接受了影像引导下的左顶叶矢状旁开颅手术。肉眼切除了一个似乎起源于硬脑膜的外在性肿瘤。无骨质受累。组织学检查显示为II级经典型软骨肉瘤，肿瘤浸润至硬脑膜。给予辅助放疗。
硬脊膜内软骨肉瘤是罕见肿瘤，大多数为间叶性。该部位的经典型软骨肉瘤更为罕见。其组织发生尚不确定。在本病例中，起源似乎是硬脑膜。由于这些肿瘤具有恶性潜能，应尽可能进行根治性切除，随后进行放疗。
