Petrova S Iu, Berzhets V M, Bystritskaia T F, Al'banova V I, Petrova N S
Mechnikov Research Institute for Vaccines and Sera, Moscow, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 2000 Sep-Oct(5):79-81.
69 patients with atopic dermatitis, aged 16-42 years, were examined. The patients were divided into two groups: group 1 consisted of patients with atopic dermatitis and bronchial asthma and/or allergic rhinitis (25 patients), group 2 consisted of patients without the respiratory syndrome (44 patients). Scarification skin tests made it possible to find out the essential difference in the sensitivity of the examinees in these two groups. In group 1 the prevalence of sensitization to house-dust mites in 23 patients (92%) with monosensitization in 8 patients (32% of the group) was observed. In group 2 sensitivity of house-dust mites was lower: it was registered in 16 patients (36%) with monosensitization in 2 patients (4% of the group). The presence of cross-sensitivity between mite allergens and Candida albicans was established. In accordance with the results of scarification skin tests, treatment included the use of antihistamine preparations, antipruritic remedies and hormonal ointments as well as the elimination of sensitizing allergens. Improvement was registered in 21 patients.
对69例年龄在16至42岁之间的特应性皮炎患者进行了检查。这些患者被分为两组:第一组由患有特应性皮炎和支气管哮喘及/或变应性鼻炎的患者组成(25例),第二组由无呼吸道综合征的患者组成(44例)。划痕皮肤试验使得能够找出这两组受检者敏感性的本质差异。在第一组中,观察到23例患者(92%)对屋尘螨致敏,其中8例患者(占该组的32%)为单一致敏。在第二组中,屋尘螨的敏感性较低:16例患者(36%)出现致敏,其中2例患者(占该组的4%)为单一致敏。已证实螨过敏原与白色念珠菌之间存在交叉敏感性。根据划痕皮肤试验结果,治疗包括使用抗组胺制剂、止痒药物和激素类软膏,以及消除致敏过敏原。21例患者病情有所改善。