Birke J A, Brandsma J W, Schreuders T A, Piefer A
Rehabilitation Services, Louisiana State University Health Sciences Center Diabetes Foot Program, 3849 North Boulevard, Baton Rouge, LA 70806, USA.
Int J Lepr Other Mycobact Dis. 2000 Sep;68(3):291-8.
Sensory testing with Semmes-Weinstein filaments was conducted on: 112 normal subjects to determine the effects of age, gender and occupation on threshold perception, 27 Hansen's disease (HD) patients to determine inter-observer and intra-observer reliability of testing, and 101 patients with HD and a history of hand and/or foot ulceration to identify thresholds for injury risk. Filament thresholds were found related to age (p < 0.002) and occupation (p < 0.001) but not gender (p > 0.1). Inter-observer and intra-observer reliability was found to be high (intraclass correlation coefficient = 0.88-0.93). The 4.93 (7.0-7.7 g) filament had 97% sensitivity and 100% specificity for identifying a history of foot injuries, and the 4.17 (1.2-1.6 g) filament had 100% sensitivity and 100% specificity for identifying hand injuries.
使用Semmes-Weinstein细丝进行感觉测试，测试对象包括：112名正常受试者，以确定年龄、性别和职业对阈值感知的影响；27名麻风病（HD）患者，以确定测试中观察者间和观察者内的可靠性；101名有手部和/或足部溃疡病史的HD患者，以确定受伤风险阈值。发现细丝阈值与年龄（p < 0.002）和职业（p < 0.001）相关，但与性别无关（p > 0.1）。观察者间和观察者内的可靠性较高（组内相关系数 = 0.88 - 0.93）。4.93（7.0 - 7.7克）的细丝对识别足部受伤史的敏感性为97%，特异性为100%；4.17（1.2 - 1.6克）的细丝对识别手部受伤的敏感性和特异性均为100%。
