Fadilah S A, Faridah I, Cheong S K
Department of Haematology and Transplantation, MAKNA-HUKM Cancer Institute, Hospital Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, 56000 Kuala Lumpur.
Med J Malaysia. 2000 Dec;55(4):513-5.
The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). The thyroid function abnormalities were not severe, short-lived and did not require specific therapy.
L-天冬酰胺酶对甲状腺的影响尚未有充分的文献记载。我们报告了首例两例在接受L-天冬酰胺酶治疗急性淋巴细胞白血病(ALL)后出现与甲状腺结节相关的甲状腺功能亢进病例。甲状腺功能异常并不严重,持续时间短,且不需要特殊治疗。