L-天冬酰胺酶治疗急性淋巴细胞白血病后出现的短暂性甲状腺功能亢进。
Transient hyperthyroidism following L-asparaginase therapy for acute lymphoblastic leukemia.
作者信息
Fadilah S A, Faridah I, Cheong S K
机构信息
Department of Haematology and Transplantation, MAKNA-HUKM Cancer Institute, Hospital Universiti Kebangsaan Malaysia, Jalan Tenteram, Cheras, 56000 Kuala Lumpur.
出版信息
Med J Malaysia. 2000 Dec;55(4):513-5.
PMID:11221167
Abstract
The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). The thyroid function abnormalities were not severe, short-lived and did not require specific therapy.
摘要
L-天冬酰胺酶对甲状腺的影响尚未有充分的文献记载。我们报告了首例两例在接受L-天冬酰胺酶治疗急性淋巴细胞白血病（ALL）后出现与甲状腺结节相关的甲状腺功能亢进病例。甲状腺功能异常并不严重，持续时间短，且不需要特殊治疗。
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