Kuznetsov V D, Bushueva O A, Rodionova E G
Antibiotiki. 1975 Jan;20(1):15-8.
Studies on variation of the streptomycin-producing organism Act. streptomycini 773 on its storage in lyophilized state showed that prolonged maintenance (for 8 years) resulted in increased percentage of "oligospore" (up to 6.9 per cent) and asporogenic (up to 6.0 per cent) variants in the population. The variants had lower transamidinase and antibiotic activity.
对产链霉素的放线菌773冻干保存过程中的变异研究表明,长期保存(8年)会导致群体中“寡孢子”变异体(高达6.9%)和无孢子变异体(高达6.0%)的比例增加。这些变异体的转脒基酶活性和抗生素活性较低。