Bunin A Ia
Vestn Oftalmol. 2000 Sep-Oct;116(5):24-7.
Trabecular endothelium and collagen fibers of the posterior wall of Schlemm's channel, obtained in sinusotrabeculectomy from patients with various stages of primary open-angle glaucoma were examined by electron microscopic and biochemical methods. Endothelial cell destruction, damage, rejection, and dissociation in intertrabecular space, progressing in severity, were observed. "Denudation" and degradation of collagen fibers and fibrils were observed. The content of lipid peroxides in aqueous humor and blocks of Schlemm's channel trabecular wall increased from stage to stage, while the level of biogenic antioxidant glutathione decreased.
采用电子显微镜和生化方法，对在鼻窦小梁切除术过程中从不同阶段原发性开角型青光眼患者获取的施莱姆管后壁小梁内皮和胶原纤维进行了检查。观察到小梁间隙内内皮细胞破坏、损伤、排斥和解离，且程度不断加重。观察到胶原纤维和原纤维的“剥脱”和降解。房水和施莱姆管小梁壁组织块中脂质过氧化物的含量逐阶段增加，而生物抗氧化剂谷胱甘肽的水平下降。
