Dorey S E, Adams G G, Lee J P, Sloper J J
Strabismus and Paediatric Service, Moorfields Eye Hospital, City Road, London EC1V 2PD, UK.
Br J Ophthalmol. 2001 Mar;85(3):310-3. doi: 10.1136/bjo.85.3.310.
To study the effects of supervised inpatient occlusion treatment for amblyopia in children who had failed to respond to outpatient treatment.
A retrospective study of 39 children admitted to a paediatric ophthalmic ward for 5 days of supervised intensive occlusion therapy having previously failed to respond to outpatient occlusion. Visual acuity of amblyopic and fellow eyes was recorded at each clinic visit before admission, daily during admission, and at each outpatient visit after discharge.
There was no significant overall improvement in visual acuity during a mean of 9 months of attempted outpatient occlusion before admission. During the 5 days of admission 26 children (67%) gained at least one line of acuity in their amblyopic eye and five (13%) gained three or more lines (mean gain 1.03 Snellen lines). The acuities of both the amblyopic and fellow eyes subsequently improved with continuing part time patching as an outpatient, including in nine of the children who did not respond during admission. At the last recorded visit, at a median time of 14 months after discharge, 13 (33%) of the patients had an acuity of at least 6/12 in their amblyopic eye.
The acuity of amblyopic eyes did not improve without effective treatment. Subsequent supervised inpatient occlusion therapy was effective in the majority of the children.
研究监督下的住院遮盖疗法对门诊治疗无效的儿童弱视的疗效。
一项回顾性研究，对39名入住小儿眼科病房接受5天监督下强化遮盖治疗的儿童进行研究，这些儿童此前门诊遮盖治疗无效。在入院前的每次门诊就诊时、住院期间每天以及出院后的每次门诊就诊时，记录弱视眼和对侧眼的视力。
入院前平均9个月的门诊遮盖治疗期间，视力无显著总体改善。在住院的5天里，26名儿童（67%）弱视眼至少提高了一行视力，5名儿童（13%）提高了三行或更多行（平均提高1.03 Snellen行）。弱视眼和对侧眼的视力随后在门诊继续进行部分时间遮盖治疗时均有所改善，包括9名住院期间无反应的儿童。在最后一次记录的就诊时，出院后中位时间为14个月，13名患者（33%）的弱视眼视力至少达到6/12。
未经有效治疗，弱视眼的视力不会改善。随后的监督下住院遮盖疗法对大多数儿童有效。
