早产儿脑室内出血的眼部意义
Ocular significance of intraventricular haemorrhage in premature infants.
作者信息
O'Keefe M, Kafil-Hussain N, Flitcroft I, Lanigan B
出版信息
Br J Ophthalmol. 2001 Mar;85(3):357-9. doi: 10.1136/bjo.85.3.357.
Abstract
AIM
To document ocular outcome in premature infants with intraventricular haemorrhages (IVH).
METHODS
68 preterm infants with IVH were examined.
RESULTS
Mean gestational age was 28.1 weeks (range 24-35). Mean birth weight was 1045.9 g (630-2240). Mean follow up was 54.6 months (6-150). IVH is graded from 1 to 4 based on the severity of haemorrhages. The incidence of ocular abnormalities was compared between low grade IVH (grade 1 and 2) and high grade IVH (grade 3 and 4). Of the 68 infants with IVH, ROP occurred in 33 infants (48.5%); 13 (43.3%) had low grade IVH; 20 (52.6%) had high grade IVH. Strabismus developed in 30 infants (44.1%); 14 (46.6%) had low grade IVH; 16 (42.1%) had high grade IVH. Infants with high grade IVH were at significant greater risk than infants with low grade IVH for the development of optic atrophy (31.5% v 16.6%), hydrocephalus (57.8% v 10%).
CONCLUSION
This study highlights the serious significance of all grades of IVH with the higher incidence of optic atrophy and hydrocephalus with high grade IVH.
摘要
目的
记录脑室出血（IVH）早产儿的眼部预后情况。
方法
对68例患有IVH的早产儿进行检查。
结果
平均胎龄为28.1周（范围24 - 35周）。平均出生体重为1045.9克（630 - 2240克）。平均随访时间为54.6个月（6 - 150个月）。IVH根据出血严重程度分为1至4级。比较了低级别IVH（1级和2级）和高级别IVH（3级和4级）患儿眼部异常的发生率。在68例患有IVH的婴儿中，33例（48.5%）发生了视网膜病变；其中13例（43.3%）为低级别IVH；20例（52.6%）为高级别IVH。30例（44.1%）出现斜视；其中14例（46.6%）为低级别IVH；16例（42.1%）为高级别IVH。高级别IVH患儿发生视神经萎缩（31.5%对16.6%）和脑积水（57.8%对10%）的风险显著高于低级别IVH患儿。
结论
本研究强调了各级IVH的严重意义，高级别IVH时视神经萎缩和脑积水的发生率更高。
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