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肝脏钝性损伤肝切除术后的问题与处理

Postoperative problems and management after hepatic resection for blunt injury to the liver.

作者信息

Vajrabukka T, Bloom A L, Sussmann M, Wood C B, Blumgart L H

出版信息

Br J Surg. 1975 Mar;62(3):189-200. doi: 10.1002/bjs.1800620306.

Abstract

The postoperative problems and management of 8 patients following right hepatic lobectomy for blunt liver injury are discussed. Multiple injury and in particular chest injury are of importance. Respiratory distress may be insidious in onset and must be anticipated. Most patients require at least temporary positive pressure ventilation. Liver regeneration is rapid and histological evidence of regenerative hyperplasia is present within 3 days of injury. Hypoglycaemia of a degree sufficient to threaten life may occur postoperatively, particularly in the first 48 hours. Jaundice may be a worrying postoperative feature, but the use of T-tube drainage after hepatic lobectomy will enable any possible extrahepatic obstruction to be excluded. Hypoproteinaemia and hypo-albuminaemia occur in the immediate postoperative period, and recovery rapidly follows the peak period of regenerative activity of the liver. Normal levels are regained by the fourth to sixth postoperative weeks. Prophylactic antibiotics have no place in the postoperative management of blunt liver injury. Haemorrhagic diathesis is common after hepatic resection and is of a complex nature. Intravascular coagulation may occur and factor V deficiency is common. The mainstay of treatment is transfusion of fresh blood.

摘要

本文讨论了8例因钝性肝损伤行右肝叶切除术后的问题及处理。多处损伤尤其是胸部损伤较为重要。呼吸窘迫可能起病隐匿,必须予以预见。大多数患者至少需要短期的正压通气。肝脏再生迅速,损伤后3天内即可出现再生性增生的组织学证据。术后可能发生足以威胁生命的低血糖,尤其是在最初48小时内。黄疸可能是令人担忧的术后表现,但肝叶切除术后使用T管引流可排除任何可能的肝外梗阻。术后即刻会出现低蛋白血症和低白蛋白血症,随着肝脏再生活动高峰期的过去,其会迅速恢复。术后第四至六周可恢复至正常水平。预防性抗生素在钝性肝损伤的术后处理中并无作用。肝切除术后出血素质常见且性质复杂。可能发生血管内凝血,且常见因子V缺乏。治疗的主要方法是输注新鲜血液。

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