大鼠雄性生殖道中硫醇分布模式和超氧化物歧化酶活性的区域差异调节精子通过附睾和输精管的运输。
Regional variations in thiol distribution pattern and superoxide dismutase activity of the male reproductive tract of the rat modulate the transport of spermatozoa through the epididymis and vas deferens.
作者信息
Chatterjee S, Laloraya M, Kumar G P
机构信息
School of Life Sciences, Devi Ahilya University, Indore, India.
出版信息
Urol Int. 2001;66(2):100-4. doi: 10.1159/000056579.
BACKGROUND
Contractile activity of the muscular coat of the epididymis wall is considered the major driving force for the propulsion of sperm through the male reproductive tract.
METHODS
Region-specific changes in the status of membrane thiols and the free radical scavening potential of the male reproductive tract of the rat were observed.
RESULTS
The present study shows that the local biochemical milieu has some influence on the transport of spermatozoa through the male reproductive tract. The vas deferens showed a higher level of superoxide dismutase activity and a low profile of thiol exposure.
CONCLUSION
We conclude that the strong scavenging potential and the lesser thiol exposure of the vas create an apparently inert vas lumen which facilitates the transit of spermatozoa through the vas.
背景
附睾管壁肌层的收缩活动被认为是精子通过雄性生殖道推进的主要驱动力。
方法
观察了大鼠雄性生殖道膜硫醇状态和自由基清除潜力的区域特异性变化。
结果
本研究表明，局部生化环境对精子通过雄性生殖道的运输有一定影响。输精管显示出较高水平的超氧化物歧化酶活性和较低的硫醇暴露情况。
结论
我们得出结论，输精管强大的清除潜力和较少的硫醇暴露形成了一个明显惰性的管腔，有利于精子通过输精管。
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