伴有功能性转移及临床甲亢的甲状腺滤泡癌

McConnon J K, von Westarp C, Mitchell R I

Can Med Assoc J. 1975 Mar 22;112(6):724-5,727.

Hyperthyroidism associated with metastatic follicular carcinoma of the thyroid gland is rare. In one patient the mass of functioning follicular tissue in the primary and metastatic tumour was so great that excessive amounts of thyroxine and triiodothyronine were produced and, as a result, clinical hyperthyroidism developed. This was in spite of the fact that the activity per unit of tissue was not supranormal and may even have been slightly subnormal. The initial response of the metastases to 131I ablative therapy was excellent.

甲状腺转移性滤泡癌相关的甲状腺功能亢进症较为罕见。在一名患者中，原发肿瘤和转移瘤中功能性滤泡组织的量非常大，以至于产生了过量的甲状腺素和三碘甲状腺原氨酸，结果出现了临床甲状腺功能亢进症。尽管每单位组织的活性并未超过正常水平，甚至可能略低于正常水平。转移灶对131I消融治疗的初始反应非常好。