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功能性转移性甲状腺癌导致的甲状腺功能亢进。治疗性放射性碘引发甲状腺危象。

Hyperthyroidism due to functioning metastatic thyroid carcinoma. Precipitation of thyroid storm with therapeutic radioactive iodine.

作者信息

Cerletty J M, Listwan W J

出版信息

JAMA. 1979 Jul 20;242(3):269-70.

PMID:448918
Abstract

Two patients had hyperthyroidism secondary to functioning metastatic follicular thyroid carcinoma. Failure to control the thyrotoxic state with antithyroid drugs in one patient prior to treatment with radioactive iodine led to exacerbation of the thyrotoxicosis with thyroid storm and death. A second patient, in whom a euthyroid state was induced before radioactive iodine therapy, had a benign posttreatment course. Radioactive iodine therapy of functioning metastatic thyroid carcinoma should be administered with caution and only after adequate preparation of the elderly patient with cardiovascular disease.

摘要

两名患者患有继发于功能性转移性滤泡状甲状腺癌的甲状腺功能亢进症。一名患者在接受放射性碘治疗前,使用抗甲状腺药物未能控制甲状腺毒症状态,导致甲状腺风暴使甲状腺毒症加重并死亡。第二名患者在放射性碘治疗前诱导出甲状腺功能正常状态,治疗后病程良好。对于功能性转移性甲状腺癌的放射性碘治疗应谨慎进行,且仅在对患有心血管疾病的老年患者进行充分准备后进行。

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