Khaw P T, Chang L, Wong T T, Mead A, Daniels J T, Cordeiro M F
Wound Healing Research Unit, Department of Pathology, Institute of Ophthalmology and Moorfields Eye Hospital, London, England.
Curr Opin Ophthalmol. 2001 Apr;12(2):143-8. doi: 10.1097/00055735-200104000-00011.
The healing process after glaucoma filtration is the main determinant of surgical failure and, even more important, the final intraocular pressure. The ability to fully control wound healing may ultimately give us the ability to set the intraocular pressure in the low teens for all patients undergoing glaucoma filtration surgery. The authors review the changes in how to use antimetabolites to improve safety, and many of the exciting new areas of progress, including growth factor neutralization and future molecular therapies to control wound healing.
青光眼滤过术后的愈合过程是手术失败的主要决定因素，更重要的是，它决定了最终的眼压。全面控制伤口愈合的能力最终可能使我们有能力为所有接受青光眼滤过手术的患者将眼压设定在略高于10的水平。作者回顾了在使用抗代谢药物以提高安全性方面的变化，以及许多令人兴奋的新进展领域，包括生长因子中和以及未来控制伤口愈合的分子疗法。
