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在具有功能性青光眼滤过手术的眼中进行白内障超声乳化术后的青光眼控制:小梁切除术与青光眼引流装置的比较。

Glaucoma control after phacoemulsification in eyes with functioning glaucoma filtration surgeries: trabeculectomies versus glaucoma drainage devices.

作者信息

Purohit Maninee, Mohite Abhijit Anand, Sung Velota C T

机构信息

Birmingham and Midland Eye Centre, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Dudley Road, Birmingham, B18 7QH, UK.

New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton Rd, Heath Town, Wolverhampton, WV10 0QP, UK.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2022 Nov;260(11):3597-3605. doi: 10.1007/s00417-022-05680-z. Epub 2022 May 6.

Abstract

PURPOSE

Several studies have demonstrated decompensation of intraocular pressure (IOP) control following phacoemulsification in eyes with a functioning trabeculectomy. Limited evidence base suggests that this effect is minimal in eyes with functioning glaucoma drainage devices (GDD). The aim of this study was to report on glaucoma control after phacoemulsification in eyes with a functioning GDD compared to eyes with a functioning trabeculectomy.

METHODS

Single-centre retrospective comparative study of patients with a functioning non-valved GDD (Baerveldt 350; Johnson & Johnson Surgical Vision) or trabeculectomy undergoing phacoemulsification. Glaucoma outcomes including IOP, cup:disc ratio (CDR), global retinal nerve fibre layer (RNFL) thickness and visual field mean deviation (MD) are reported. Failure was defined as IOP rise > 20% from baseline.

RESULTS

Fifteen eyes with a functioning trabeculectomy and twenty-three eyes with a functioning GDD with 24-month post-phacoemulsification data were identified. Mean IOPs were significantly lower in the trabeculectomy group at month 24 compared to the GDD group, 9.5 and 15.9 mmHg (p = 0.001) respectively. At month 12, there was significant worsening on MD in GDD group compared to trabeculectomy group, - 20.0 dB and - 11.3 dB respectively (p = 0.03). A greater proportion of eyes failed in the GDD group compared to the trabeculectomy group, N = 15 (65%) and n = 7 (47%), p = 0.26.

CONCLUSION

As with functioning trabeculectomies, phacoemulsification should be approached with similar caution in eyes with functioning GDD. An existing GDD is at least as likely to fail following clear corneal phacoemulsification as an existing trabeculectomy and non-augmented GDDs may be at greater risk.

摘要

目的

多项研究表明,在小梁切除术功能正常的眼中,白内障超声乳化术后眼压(IOP)控制出现失代偿。有限的证据表明,这种影响在青光眼引流装置(GDD)功能正常的眼中最小。本研究的目的是报告与小梁切除术功能正常的眼相比,GDD功能正常的眼白内障超声乳化术后的青光眼控制情况。

方法

对接受白内障超声乳化术的功能性无瓣GDD(Baerveldt 350;强生手术视觉公司)或小梁切除术患者进行单中心回顾性比较研究。报告青光眼相关结果,包括眼压、杯盘比(CDR)、视网膜神经纤维层(RNFL)整体厚度和视野平均缺损(MD)。失败定义为眼压较基线升高>20%。

结果

确定了15只小梁切除术功能正常的眼和23只GDD功能正常的眼,这些眼有白内障超声乳化术后24个月的数据。与GDD组相比,小梁切除术组在第24个月时的平均眼压显著更低,分别为9.5 mmHg和15.9 mmHg(p = 0.001)。在第12个月时,与小梁切除术组相比,GDD组的MD显著恶化,分别为-20.0 dB和-11.3 dB(p = 0.03)。与小梁切除术组相比,GDD组失败的眼比例更高,分别为N = 15(65%)和n = 7(47%),p = 0.26。

结论

与功能正常的小梁切除术一样,对于GDD功能正常的眼,白内障超声乳化术也应同样谨慎进行。现有的GDD在透明角膜白内障超声乳化术后至少与现有的小梁切除术一样容易失败,且未增强的GDD可能风险更大。

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