Jereb B, Stjernswärd J, Löwhagen T
Cancer. 1975 May;35(5):1293-5. doi: 10.1002/1097-0142(197505)35:5<1293::aid-cncr2820350504>3.0.co;2-w.
In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an additional 8 patients also treated with methotrexate indicate a positive therapeutic effect, the mean survival time being 9.4 months. Disappearance of recurrent tumor or pulmonary metastases was noted in 2 patients.
在79例经组织学证实的间变性巨细胞癌患者中，记录了其症状、治疗方法及预后情况。78例患者死亡，平均生存时间为2.5个月。1例患者治愈。得出的结论是，单纯手术和/或放疗并不足够。另外8例接受甲氨蝶呤治疗的患者结果显示有积极的治疗效果，平均生存时间为9.4个月。2例患者出现复发肿瘤或肺转移消失。
