Michel S, Hohenleutner U, Stolz W, Knüchel-Clarke R, Helmig M, Landthaler M
Dermatologische Klinik und Poliklinik der Universität Regensburg.
Klin Padiatr. 2001 Jan-Feb;213(1):39-42. doi: 10.1055/s-2001-11273.
We present a 2-year-old boy with a red, cutaneous-subcutaneous, nodule on the right elbow and a 2.5 year-old girl with an red-brown, indurated plaque on the left knee. Colour-coded doppler sonography of the boy's lesion showed vascular structures. A biopsy established the diagnosis of tufted angioma in both patients. Tufted angioma is clinically characterized by slowly spreading erythematous macules and plaques preferentially located on the upper trunk and neck in children. It is a benign tumor, malignant transformation has not been reported. The case history, clinical and histological findings contribute to the diagnosis. Tufted angioma has to be distinguished from Kaposi's sarcoma, angiosarcoma, hemangioma of infancy, sometimes bacillary angiomatosis and other cutaneous capillary malformations. Treatment of tufted angioma is difficult, various modalities like glucocorticosteroids, Interferon-alpha, flashlamp-pumped pulsed dye laser, excision and spontaneous regression have been described with varying results.
我们报告了一名2岁男孩，其右肘部有一个红色的皮肤 - 皮下结节，以及一名2.5岁女孩，其左膝有一个红棕色的硬结斑块。对男孩病变进行的彩色编码多普勒超声检查显示有血管结构。活检确诊两名患者均为簇状血管瘤。簇状血管瘤的临床特征为缓慢扩散的红斑和斑块，在儿童中优先位于上躯干和颈部。它是一种良性肿瘤，尚未有恶变的报道。病史、临床和组织学发现有助于诊断。簇状血管瘤必须与卡波西肉瘤、血管肉瘤、婴儿血管瘤、有时还有杆菌性血管瘤及其他皮肤毛细血管畸形相鉴别。簇状血管瘤的治疗困难，已描述了多种治疗方式，如糖皮质激素、α干扰素、闪光灯泵浦脉冲染料激光、手术切除及自然消退，但其效果各异。
