Bonno S, Raschilas F, Mari I, Pigne E, Pouchot J, De Broucker F, Vinceneux P
Service de Médecine interne V, Hôpital Louis Mourier, 178, rue des Renouillers, F 92700 Colombes.
Presse Med. 2001 Jan 27;30(3):115-8.
Klüver-Bucy syndrome (KBS) is an infrequent condition that includes, in its complete form, often massive amnesia, psychic blindness (so-called visual agnosia), oral tendencies, hypermetamorphosis, changes in emotional behavior and increased sexual activity. Anatomic lesions in KBS involve the temporal lobe cortex bilaterally, and the amygdala as well as temporal white matter.
A 17-year-old patient treated for herpetic meningoencephalitis developed neuropsychological signs leading to the diagnosis of Klüver-Bucy syndrome.
KBS can occur in various clinical conditions but herpetic encephalitis is the most frequent cause. KBS may be transient or partially regressive, but severe amnesia that may progress to Korsakoff syndrome is often persistent after herpetic encephalitis. Neuroleptics or carbamazepine can be used for symptomatic treatment.
克吕弗-布西综合征（KBS）是一种罕见病症，其完整形式通常包括严重失忆、精神性盲（即所谓的视觉失认症）、口欲倾向、变换反应、情绪行为改变及性活动增加。KBS的解剖学病变双侧累及颞叶皮质、杏仁核以及颞叶白质。
一名17岁因疱疹性脑膜脑炎接受治疗的患者出现神经心理学体征，最终诊断为克吕弗-布西综合征。
KBS可发生于多种临床情况，但疱疹性脑炎是最常见病因。KBS可能是短暂性的或部分可逆的，但疱疹性脑炎后常持续存在可能进展为科萨科夫综合征的严重失忆。可使用抗精神病药物或卡马西平进行对症治疗。
