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[距骨骨软骨损伤的自体软骨-骨移植手术治疗]

[Operative therapy of osteochondral lesions of the talus with autologous cartilage-bone transplantation].

作者信息

Schöttle P B, Oettl G M, Agneskirchner J D, Imhoff A B

机构信息

Abteilung und Poliklinik für Sportorthopädie TU München, Connollystrasse 32 80809 München.

出版信息

Orthopade. 2001 Jan;30(1):53-8. doi: 10.1007/s001320050573.

Abstract

Since 1996 we have gained experience in the development and clinical application of the OATS technique in 167 cases. Operative management, technical demands and early results of osteochondral cylindrical autograft plugs at the talus are presented. Between April 1996 and November 2000 we treated 39 patients (21 male, 18 female) with an average age of 28.4 years (range: 16-57 years) for osteochondral defects with an average size of 8 x 15 mm-20 x 15 mm at the medial (n = 31) and lateral (n = 6) talar dome as well as at the distal tibia (n = 2) with an OATS technique. Indications were osteochondral defects after trauma in 12 patients (med., n = 5; lat., n = 5; dist. tibia n = 2) and osteochondrosis dissecans (grades III and IV) in 27 patients (med., n = 26; lat., n = 1). The donor site was the proximal lateral femoral condyle in all patients. An additional osteotomy of the malleolus was necessary in 30 patients. All patients were scored pre- and postoperatively by a Lysholm Bruns score and monitored by postoperative MRI. The follow-up extended for an average of 19.6 months (6-42). The Lysholm score for all patients rose from 62 points (range: 20-77) up to 92 points (range: 63-100). There was no correlation between patients with and without an osteotomy of the malleolus. The postoperative MRI showed a complete incorporation and vitality of the transplanted cylinders as well as a congruence of the joint surface. Complications were pain in three cases in the region of the osteotomy, which decreased after removal of the screws, and synovialitis in one case. One patient reported femoropatellar pain for about 4 weeks. The OATS technique achieves encouraging results in limited osteochondral defects in the talar dome even in preoperated osteochondral defects. Because of the mostly posterior localization of the defect zone, osteotomy of the malleolus is necessary in most cases. Harvesting the donor cylinders from the ipsilateral knee joint by mini-arthrotomy shows a low mortality. The OATS technique is a suitable, causal and cost-effective therapy, which can possibly prevent and at least delay the development of an arthrosis.

摘要

自1996年以来,我们在167例患者中积累了运用OATS技术的开发及临床应用经验。本文介绍了距骨骨软骨圆柱状自体移植栓的手术管理、技术要求及早期结果。1996年4月至2000年11月,我们采用OATS技术治疗了39例患者(男21例,女18例),平均年龄28.4岁(范围:16 - 57岁),其距骨内侧(n = 31)、外侧(n = 6)穹窿以及胫骨远端(n = 2)存在平均大小为8×15mm - 20×15mm的骨软骨缺损。适应症包括12例创伤后骨软骨缺损患者(内侧,n = 5;外侧,n = 5;胫骨远端,n = 2)以及27例剥脱性骨软骨炎(III级和IV级)患者(内侧,n = 26;外侧,n = 1)。所有患者的供骨部位均为股骨外侧髁近端。30例患者需要额外进行踝关节截骨术。所有患者术前及术后均采用Lysholm Bruns评分进行评估,并通过术后MRI进行监测。随访平均时长为19.6个月(6 - 42个月)。所有患者的Lysholm评分从62分(范围:20 - 77分)提高到了92分(范围:63 - 100分)。是否进行踝关节截骨术的患者之间无相关性。术后MRI显示移植圆柱完全融合且具有活力,关节面平整。并发症包括3例截骨部位疼痛,取出螺钉后疼痛减轻,以及1例滑膜炎。1例患者报告髌股关节疼痛约4周。即使是术前已存在骨软骨缺损的情况,OATS技术在距骨穹窿有限的骨软骨缺损治疗中也取得了令人鼓舞的结果。由于缺损区域大多位于后方,多数情况下需要进行踝关节截骨术。通过微型关节切开术从同侧膝关节获取供体圆柱显示死亡率较低。OATS技术是一种合适的、有针对性且具有成本效益的治疗方法,可能预防并至少延缓关节病的发展。

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