Tabarov M S
Institute of Experimental Medicine, Russian Acad. Med. Sci, 197376, St. Petersburg, Acad. I. P. Pavlov St., 12.
Ross Fiziol Zh Im I M Sechenova. 2001 Jan;87(1):43-9.
In 12 anesthetized cats both hypoxia and hypothermia enhanced the shifts in arterial resistance against blood flow in response to noradrenaline and diminished the shifts in response to isoproterenol. Combination of both stress factors considerably weakened the adrenergic vasoconstriction and rather little affected the adrenergic vasodilatation. The findings suggest that protective effect of hypothermia against the background of a hypoxic stress might be a mechanism preventing disorders in the tissue metabolism.
在12只麻醉猫中，缺氧和低温均增强了去甲肾上腺素引起的动脉血流阻力变化，并减弱了异丙肾上腺素引起的变化。两种应激因素共同作用时，显著减弱了肾上腺素能血管收缩，而对肾上腺素能血管舒张影响较小。这些发现表明，在缺氧应激背景下低温的保护作用可能是一种防止组织代谢紊乱的机制。
