Hellriegel B
Zoological Museum, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland.
Trends Parasitol. 2001 Feb;17(2):102-6. doi: 10.1016/s1471-4922(00)01767-0.
'Immunoepidemiology' combines individual- and population-oriented approaches to create new perspectives. It examines how inter-individual differences in immune responses affect the population dynamics of micro- and macro-parasites to produce the epidemiological patterns of infection observed in heterogeneous host populations. Here, I discuss how research has only just begun to tap the potential of this integrative discipline that incorporates immunology, parasitology, genetics, epidemiology, ecology, mathematical modelling and statistics.
“免疫流行病学”结合了以个体和群体为导向的方法,以创造新的视角。它研究免疫反应中的个体差异如何影响微观和宏观寄生虫的种群动态,从而在异质宿主种群中产生观察到的感染流行病学模式。在此,我将探讨该研究如何才刚刚开始挖掘这一综合学科的潜力,该学科融合了免疫学、寄生虫学、遗传学、流行病学、生态学、数学建模和统计学。