Eriksson M, Nilsson B, Modig J, Acosta R, Johansson B, Larsson A
Anestesi- och intensivvårdskliniken, Akademiska sjukhuset, Uppsala.
Lakartidningen. 2001 Jan 31;98(5):439-42.
Hypotensive reactions during surgical procedures cause diagnostic problems in establishing whether the hypotension is due to blood loss or pharmaceuticals or other causes. A case of hypotension probably due to an albumin infusion is described. Bradykinin effects are probably the cause of many hypotensive reactions. Angiotensin-converting enzyme (ACE) inhibitors reduce degradation of bradykinin and thus increase the risk of hypotensive reactions. When possible, doctors should consider withholding ACE inhibitors 24 hours before surgical procedures likely to require albumin transfusions.
手术过程中的低血压反应在确定低血压是由失血、药物还是其他原因引起时会导致诊断问题。本文描述了一例可能因输注白蛋白导致的低血压病例。缓激肽效应可能是许多低血压反应的原因。血管紧张素转换酶（ACE）抑制剂会减少缓激肽的降解，从而增加低血压反应的风险。在可能的情况下，医生应考虑在可能需要输注白蛋白的手术前24小时停用ACE抑制剂。
