Goel A, Joseph S, Dutta T K
Department of Medicine, JIPMER, Pondicherry.
J Assoc Physicians India. 1998 Sep;46(9):786-90.
The present study evaluated 103 consecutive patients of organophosphate poisoning with special reference to the need for ventilatory support. Of 103 patients, 36(34.95%) required assisted ventilation. The need for ventilatory support was significantly more with greater time duration for institution of specific treatment, low level of sensorium at admission, pin-point pupils and generalized fasciculations, presence of convulsions, presence of respiratory insufficiency at admission, and higher initial atropine requirement for atropinization. The study also proposes a system of grading of severity, modified from the existing systems proposed.
本研究评估了103例连续的有机磷中毒患者,特别关注通气支持的需求。在103例患者中,36例(34.95%)需要辅助通气。特定治疗开始的时间越长、入院时意识水平低、针尖样瞳孔和全身性肌束震颤、存在惊厥、入院时存在呼吸功能不全以及达到阿托品化所需的初始阿托品剂量越高,通气支持的需求就显著增加。该研究还提出了一种严重程度分级系统,是在现有系统基础上修改而来的。