Biagioni E, Mercuri E, Rutherford M, Cowan F, Azzopardi D, Frisone M F, Cioni G, Dubowitz L
Department of Paediatrics and Neonatal Medicine, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom.
Pediatrics. 2001 Mar;107(3):461-8. doi: 10.1542/peds.107.3.461.
The electroencephalogram (EEG) is widely used in full-term infants with acute neonatal encephalopathy, and its prognostic value has been confirmed by several studies. Magnetic resonance imaging (MRI) of the brain has also been applied in these patients, and increasing numbers of reports affirm its prognostic reliability. The aim of this study has been to investigate the correlation between an early EEG and MRI findings in infants with acute neonatal encephalopathy and to assess the prognostic value of a combination of EEG and MRI findings.
Twenty-five full-term infants had an EEG recorded within the first 72 hours after birth and a neonatal brain MRI scan after the end of the first week.
Both EEG and MRI were predictive of outcome. A normal MRI was always associated with normal EEG background activity and normal outcome and severe abnormalities on MRI with marked EEG abnormalities and an abnormal outcome. When the MRI showed moderate abnormalities, the EEG in all cases but one identified patients with normal and abnormal outcome.EEG, MRI, HIE, neurodevelopment.
脑电图（EEG）广泛应用于患有急性新生儿脑病的足月儿，其预后价值已得到多项研究证实。脑部磁共振成像（MRI）也已应用于这些患者，越来越多的报告证实了其预后可靠性。本研究的目的是探讨急性新生儿脑病患儿早期脑电图与MRI表现之间的相关性，并评估脑电图和MRI表现相结合的预后价值。
25名足月儿在出生后72小时内进行了脑电图记录，并在第一周结束后进行了新生儿脑部MRI扫描。
脑电图和MRI均能预测预后。正常的MRI总是与正常的脑电图背景活动和正常预后相关，而MRI上的严重异常与明显的脑电图异常和异常预后相关。当MRI显示中度异常时，除1例患者外，所有病例的脑电图均能识别出预后正常和异常的患者。脑电图、MRI、新生儿缺氧缺血性脑病、神经发育。
