Quint L E, Williams D M, Francis I R, Monaghan H M, Sonnad S S, Patel S, Deeb G M
Department of Radiology, University of Michigan Health System, Box 0030, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0030, USA.
Radiology. 2001 Mar;218(3):719-23. doi: 10.1148/radiology.218.3.r01mr24719.
To document the natural history of ulcerlike aortic lesions and determine whether any computed tomographic (CT) features predict outcome.
CT scans from 1994 to 1998 that depicted an ulcerlike aortic lesion were retrospectively evaluated. Features evaluated included lesion and aortic size and intramural hematoma. Initial CT findings were correlated with clinical data and subsequent CT findings.
There were 56 lesions in 38 patients. Follow-up (mean, 18.4 months) CT scans were available for 33 lesions. Stability of the lesion and adjacent aorta was noted in 21 lesions. Two lesions were unchanged, although associated intramural hematoma regressed over 1-2 months. Ten lesions showed mild to moderate increase in aortic diameter (mean follow-up, 19.8 months) either with (seven lesions) or without (one lesion) increase in size of the lesion or with incorporation of the lesion into the aortic wall contour (two lesions). Of all 56 lesions, 37 were clinically stable, two were associated with recurrent chest and/or back pain, eight underwent surgical resection or stent placement, and two were in patients who died. Seven lesions were in patients lost to follow-up. No initial CT feature was predictive of CT outcome, although lack of pleural effusion correlated with clinical stability.
Most ulcerlike aortic lesions are asymptomatic and do not enlarge. About one-third of lesions progress, generally resulting in mild interval aortic enlargement.
记录溃疡样主动脉病变的自然病程,并确定是否有任何计算机断层扫描(CT)特征可预测其预后。
回顾性评估1994年至1998年期间显示溃疡样主动脉病变的CT扫描图像。评估的特征包括病变及主动脉大小和壁内血肿。将初始CT表现与临床数据及后续CT表现进行关联分析。
38例患者共有56处病变。对其中33处病变进行了随访(平均18.4个月)CT扫描。21处病变的病变及相邻主动脉保持稳定。2处病变无变化,但其相关壁内血肿在1 - 2个月内消退。10处病变的主动脉直径有轻度至中度增加(平均随访19.8个月),其中7处病变大小增加,1处病变大小未增加,2处病变被纳入主动脉壁轮廓。在所有56处病变中,37处临床稳定,2处伴有复发性胸痛和/或背痛,8处接受了手术切除或支架置入,2处患者死亡。7处病变患者失访。尽管无胸腔积液与临床稳定相关,但初始CT特征均无法预测CT结果。
大多数溃疡样主动脉病变无症状且不增大。约三分之一的病变会进展,通常导致主动脉轻度间歇性增大。