Anguera I, Quaglio G, Miró J M, Paré C, Azqueta M, Marco F, Mestres C A, Moreno A, Pomar J L, Mezzelani P, Sanz G
Cardiovascular Institute, Department of Microbiology, Institut d'Investigacions Biomèdiques August Pi I Sunyer-Hospital Clinic, University of Barcelona, Spain.
Am J Cardiol. 2001 Mar 1;87(5):652-4, A10. doi: 10.1016/s0002-9149(00)01449-1.
This study sought to determine the clinical and echocardiographic features, surgical approach, and outcome of patients with infective endocarditis complicated with aortocardiac fistulas among a series of 346 consecutive cases between 1988 and 1998. Nine patients (2%) were found to have aortocardiac fistulas complicating infective endocarditis caused by highly pyogenic pathogens (4 patients had ruptured abscesses of the right sinus of Valsalva, 3 had fistulous communications from the left coronary sinus, and 1 had a fistulized abscess in the noncoronary sinus). Mortality in these patients was very high (55%), even when surgery was attempted early in the course of the disease and reconstructive procedures were implemented.
本研究旨在确定1988年至1998年间连续346例感染性心内膜炎患者中合并主动脉-心脏瘘患者的临床和超声心动图特征、手术方式及预后。发现9例(2%)患者合并由高致病性病原体引起的感染性心内膜炎相关的主动脉-心脏瘘(4例患者有瓦尔萨尔瓦右窦脓肿破裂,3例有来自左冠状窦的瘘管交通,1例在无冠状窦有瘘管化脓肿)。即使在疾病早期尝试手术并实施重建手术,这些患者的死亡率仍非常高(55%)。