Ruzicka K, Veitl M, Thalhammer-Scherrer R, Schwarzinger I
Department of Laboratory Medicine, University of Vienna, Austria.
Arch Pathol Lab Med. 2001 Mar;125(3):391-6. doi: 10.5858/2001-125-0391-TNHASX.
The new hematology analyzer Sysmex XE-2100 (TOA Medical Electronics, Kobe, Japan) has a novel, combined, white blood cell differential technology and a special reagent system to enumerate nucleated red blood cells.
Performance evaluation of both technologies of the Sysmex XE-2100 according to the H20-A protocol of the National Committee for Clinical and Laboratory Standards and comparison of the results with those for the hematology analyzer Sysmex NE-8000 (TOA Medical Electronics).
Five hundred forty-four blood samples randomly chosen from various inpatient and outpatient departments of the Vienna University hospital.
Five-part white blood cell differential counts on the XE-2100 revealed excellent correlation with the manual reference method for neutrophils, lymphocytes, and eosinophils (r =.925,.922, and.877, respectively) and good correlation for monocytes and basophils (r =.756 and.763, respectively). The efficiency rates of flagging for the presence of >/=1% abnormal white blood cells were 83% (XE-2100) and 66% (NE-8000). The correlation of automated and microscopic nucleated red blood cell counts was excellent (r =.97).
From the present evaluation and our former experience with other types of Sysmex analyzers, we conclude that the new white blood cell differential technology of the XE-2100 represents a further development toward more efficient flagging of abnormal white blood cells.
新型血液分析仪Sysmex XE - 2100（日本神户东亚医用电子株式会社）拥有一种新颖的、组合式的白细胞分类技术以及一种特殊的试剂系统，用于对有核红细胞进行计数。
根据美国国家临床和实验室标准委员会的H20 - A方案对Sysmex XE - 2100的两种技术进行性能评估，并将结果与血液分析仪Sysmex NE - 8000（日本神户东亚医用电子株式会社）的结果进行比较。
从维也纳大学医院各住院部和门诊部随机选取544份血样。
XE - 2100上的五分类白细胞计数显示，中性粒细胞、淋巴细胞和嗜酸性粒细胞与手工参考方法具有极好的相关性（r分别为0.925、0.922和0.877），单核细胞和嗜碱性粒细胞具有良好的相关性（r分别为0.756和0.763）。对于存在≥1%异常白细胞的标记效率，XE - 2100为83%，NE - 8000为66%。自动计数与显微镜下有核红细胞计数的相关性极好（r = 0.97）。
从目前的评估以及我们之前使用其他型号Sysmex分析仪的经验来看，我们得出结论，XE - 2100的新型白细胞分类技术代表了在更高效标记异常白细胞方面的进一步发展。
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