Nakul-Aquaronne Danièle, Sudaka-Sammarcelli Isabelle, Ferrero-Vacher Corinne, Starck Benoit, Bayle Jacques
Laboratoire Central d'Hématologie, Hôpital de Cimiez, Nice, France.
J Clin Lab Anal. 2003;17(4):113-23. doi: 10.1002/jcla.10083.
The Sysmex XE-2100 (Sysmex Corp. Kobe, Japan) is a latest-generation hematology analyzer. Its optical and electrical measuring technology is improved by the addition of flux cytometry, fluorescence, and differential lysis. Its analytical performance in terms of precision, reproducibility, linearity, carryover, and time stability was found to be entirely satisfactory. In addition, the results of 500 complete blood counts and differentials correlated perfectly with those obtained by the Coulter STKS (Beckman Coulter, Villapointe, France). The comparison of 500 leukocyte differential count results analyzed in parallel with optical microscopy and the XE-2100 were surprising, and favorable to the XE-2100. This analyzer provides the user with an undeniable feeling of security concerning its reliability in detecting and identifying anomalies in the automated leukocyte differential count. With a sensitivity of 96%, a negative predictive value (NPV) of 98%, and a false-negative (FN) rate of 4%, the XE-2100 has perhaps reached the technological limits for a machine performing morphological recognition of normal and pathological blood cells.
希森美康XE - 2100（日本神户希森美康公司）是一款新一代血液分析仪。通过添加流式细胞术、荧光技术和差别溶解技术，其光学和电学测量技术得到了改进。在精密度、重现性、线性、携带污染和时间稳定性方面，其分析性能完全令人满意。此外，500例全血细胞计数和分类结果与库尔特STKS（法国维拉波因特贝克曼库尔特公司）获得的结果完全相关。将500例白细胞分类计数结果与光学显微镜和XE - 2100并行分析的比较结果令人惊讶，且对XE - 2100有利。该分析仪在自动白细胞分类计数中检测和识别异常的可靠性方面，给用户提供了一种不可否认的安全感。希森美康XE - 2100灵敏度为96%，阴性预测值（NPV）为98%，假阴性（FN）率为4%，可能已达到对正常和病理血细胞进行形态识别的机器的技术极限。
