[胰岛素依赖型糖尿病患儿治疗期间红细胞膜脂质成分及其生物物理参数]
[Composition of erythrocyte membrane lipids and their biophysical parameters in children with insulin-dependent diabetes during therapy].
作者信息
Kolosova M V, Novitskiĭ V V, Stepovaia E A
出版信息
Klin Lab Diagn. 2001 Jan(1):10-2.
PMID:11233266
Abstract
Chronic secondary hyperglycemia in children with insulin insufficiency is characterized by quantitative and qualitative changes in membrane lipid spectrum and increased microviscosity of deep layers of peripheral blood erythrocyte membrane lipid bilayer. Traditional combined therapy does not normalize these parameters, which can lead to vascular complications in children with insulin-dependent diabetes mellitus.
摘要
胰岛素分泌不足儿童的慢性继发性高血糖症的特征在于膜脂质谱的定量和定性变化以及外周血红细胞膜脂质双层深层微粘度增加。传统的联合治疗无法使这些参数恢复正常，这可能导致胰岛素依赖型糖尿病儿童出现血管并发症。
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