Maksina A G, Mikaélian N P, Kniazev Iu A, Daĭniak B A
Biofizika. 1992 Mar-Apr;37(2):306-9.
Microviscosity and polarity of erythrocyte membranes of the blood of patients suffering from diabetes were studied by ESR using spin-labeled fatty acids. Structural changes were discovered 0.6-0.8 nm from the membrane surface in the lipid bilayer of erythrocytes obtained from patients' blood. No essential immobilization of the acyl chains of phospholipids was found in deeper layers as compared with the control. The bilayer polarity at different depth was not essentially changed either.
利用自旋标记脂肪酸,通过电子自旋共振(ESR)研究了糖尿病患者血液中红细胞膜的微粘度和极性。在从患者血液中获取的红细胞脂质双层中,发现距膜表面0.6 - 0.8纳米处有结构变化。与对照组相比,在更深层未发现磷脂酰基链有明显的固定化现象。不同深度处的双层极性也基本未发生变化。