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[苯二氮䓬类药物和苯二氮䓬受体激动剂在睡眠障碍治疗中的作用及风险。临床医学视角的评估]

[Benzodiazepines and benzodiazepine receptor agonists in the treatment of sleep disorders--importance and dangers. Evaluation from the clinical medical view].

作者信息

Bauer U

机构信息

Klinik für Psychiatrie der Hans-Berger-Kliniken des Klinikums der Friedrich-Schiller-Universität Jena.

出版信息

Z Arztl Fortbild Qualitatssich. 2001 Jan;95(1):17-21.

PMID:11233488
Abstract

After first giving an overview about the epidemiological situation, the indications and contraindications of benzodiazepines as well as those of the newer short-time hypnotics zolpidem and zopiclone are reviewed. Premises for their use and alternatives to their application are discussed and the different substances are discussed for their clinical use. Problems of drug abuse and addiction are accounted in detail for these effective and little toxic agents. Finally recommendations for treatment are given to contribute to a more critical and scientific way of prescribing these valuable, though problematic, drugs.

摘要

在首先概述了流行病学情况之后,回顾了苯二氮䓬类药物以及新型短效催眠药唑吡坦和佐匹克隆的适应证和禁忌证。讨论了它们的使用前提和应用替代方法,并探讨了不同药物的临床用途。对于这些有效且毒性较小的药物,详细阐述了药物滥用和成瘾问题。最后给出了治疗建议,以促进更审慎、科学地开具这些虽有问题但很有价值的药物的处方。

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[Benzodiazepines and benzodiazepine receptor agonists in the treatment of sleep disorders--importance and dangers. Evaluation from the clinical medical view].[苯二氮䓬类药物和苯二氮䓬受体激动剂在睡眠障碍治疗中的作用及风险。临床医学视角的评估]
Z Arztl Fortbild Qualitatssich. 2001 Jan;95(1):17-21.
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Tidsskr Nor Laegeforen. 2010 Mar 25;130(6):610-2. doi: 10.4045/tidsskr.09.0687.
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[New non-benzodiazepine hypnotics. Progress in therapy of sleep disorders?].[新型非苯二氮䓬类催眠药。睡眠障碍治疗取得进展了吗?]
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[Benzodiazepine: long term use and addiction].[苯二氮䓬类药物:长期使用与成瘾]
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Pharmacologic treatment of disturbed sleep in the elderly.老年人睡眠障碍的药物治疗。
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Paradoxical reactions to benzodiazepines in intravenous sedation: a report of 2 cases and review of the literature.静脉镇静中苯二氮䓬类药物的反常反应:2例报告及文献复习
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引用本文的文献

1
[High usage of zolpidem and zopiclone. Cross-sectional study using claims data].[唑吡坦和佐匹克隆的高使用率。使用理赔数据的横断面研究]
Nervenarzt. 2008 Jan;79(1):67-72. doi: 10.1007/s00115-007-2280-6.