Fauteck J D
Fis International, Kalletal.
Z Arztl Fortbild Qualitatssich. 2001 Jan;95(1):39-43.
Melatonin, the hormone of the pineal gland, is under discussion as multipotent hormone for different indications. The question whether there is a therapeutical benefit for all these indications could not be evaluated, because more clinical studies are needed. Based on the data of basic research as well as first clinical experience, the use of melatonin to treat sleep disorders caused by a deficit of melatonin might be appropriate. Other indications, derived from animal studies where the results often could not be applied to humans, have still to be proved. Given the fact that melatonin is not an approved product, only an intent to treat approach is allowed where it might by useful to document the melatonin deficit and to use a selected and certificate product.
褪黑素，即松果体分泌的激素，正作为一种针对不同适应症的多效激素进行讨论。由于需要更多的临床研究，所以无法评估其对所有这些适应症是否具有治疗益处。基于基础研究数据以及初步临床经验，使用褪黑素治疗因褪黑素缺乏引起的睡眠障碍可能是合适的。其他适应症源于动物研究，而这些研究结果往往无法应用于人类，仍有待证实。鉴于褪黑素并非获批产品，仅允许采用意向性治疗方法，在此过程中记录褪黑素缺乏情况并使用经过挑选和认证的产品可能会有所帮助。
