Whicher J T, Davies J D, Grayburn J A
J Clin Pathol. 1975 Jan;28(1):54-9. doi: 10.1136/jcp.28.1.54.
A patient is described with myeloma without paraproteinaemia or Bence Jones proteinuria in whom the tumour cells have been shown to contain monoclonal immunoglobulin. The use of immunoelectrophoresis and polyacrylamide gel electrophoresis has established, apparently for the first time, that the immunoglobulin components are present in the form of intact molecules and free light chains.
本文描述了一名骨髓瘤患者，其无副蛋白血症或本-周蛋白尿，但其肿瘤细胞已被证实含有单克隆免疫球蛋白。免疫电泳和聚丙烯酰胺凝胶电泳的应用，显然首次证实免疫球蛋白成分以完整分子和游离轻链的形式存在。
