Mahamedi H, André M, Privat C, Delèvaux I, D'Incan M, Piette J C, Francès C, Aumaître O
Service de médecine interne, hôpital Gabriel-Montpied, BP 69, 63003 Clermont-Ferrand, France.
Rev Med Interne. 2001 Feb;22(2):132-40. doi: 10.1016/s0248-8663(00)00303-9.
Henoch-Schonlein purpura is a rare eventuality in adulthood. Abdominal involvement can worsen the short-term prognosis and justify medical treatment to avoid surgery.
Abdominopelvic computed tomography (CT) was performed in six adult patients (four men and two women; age range, 19-74 years) with Henoch-Schonlein purpura before any treatment. Abdominal symptoms were concomitant with the purpuric rash in two cases and followed it in the other cases.
The small bowel was always involved with a parietal thickening, and the target sign was observed in three patients. The lesions were located in the duodenum in two patients, the jejunum in two and the ileum in five. Two segments were involved in one patient and three segments in another patient. A peritoneal effusion was always present. No colonic lesion was discovered on CT. Once the results were known, all patients received steroids with initially intravenous methylprednisolone in five patients at doses ranging from 80 to 1,000 mg/day. On follow-up, none of the patients underwent surgery.
Abdominopelvic CT scan demonstrated signs suggestive of intestinal vasculitis. An underlying neoplasia or an eventual other cause of abdominal pain were explored and a steroid therapy was then began with a good outcome. Abdominal CT can be helpful in the diagnosis of abdominal involvement in Henoch-Schonlein purpura.
成人患过敏性紫癜实属罕见。腹部受累会使短期预后恶化,且有必要进行药物治疗以避免手术。
对6例成年过敏性紫癜患者(4例男性,2例女性;年龄范围19 - 74岁)在接受任何治疗前进行腹盆腔计算机断层扫描(CT)。2例患者腹部症状与紫癜疹同时出现,其他患者则在紫癜疹之后出现。
小肠均有受累,表现为肠壁增厚,3例患者可见靶征。病变位于十二指肠的有2例患者,空肠的有2例,回肠的有5例。1例患者累及2段肠管,另1例患者累及3段肠管。均存在腹腔积液。CT检查未发现结肠病变。得知检查结果后,所有患者均接受了类固醇治疗,5例患者最初静脉注射甲泼尼龙,剂量为80至1000毫克/天。随访期间,所有患者均未接受手术。
腹盆腔CT扫描显示出提示肠道血管炎的征象。排查了潜在的肿瘤或腹痛的其他可能病因,随后开始类固醇治疗,效果良好。腹部CT有助于诊断过敏性紫癜的腹部受累情况。