Lepori M, Bochud P Y, Owlya R, Broccard A, Schaller M D
Division de soins intensifs de médecine, Service B, Département de médecine, CHUV, rue du Bugnon, 1011 Lausanne.
Rev Med Suisse Romande. 2001 Jan;121(1):47-50.
Endocarditis is a common disease in hospital practice. Identification of the microorganism responsible for the valvular damage is essential to establish the prognosis and to determine the optimal antibiotic treatment. In some cases of endocarditis the diagnosis is laborious, especially when the responsible microorganism is difficult to detect using standard culture techniques. Here we report a case of native aortic valve endocarditis due to Kingella kingae, a Gram negative organism of the HACEK group. In addition we review 6 other cases of endocarditis caused by organism belonging to this group, treated in our hospital between 1983 and 1999. Epidemiological studies show that less than 5% of all cases of endocarditis are caused by organisms of the HACEK group. The diagnosis is often delayed because their slow growth on a standard culture medium. We describe clinical and microbiological characteristics of this group of endocarditis.
心内膜炎是医院临床实践中的常见疾病。确定导致瓣膜损害的微生物对于判断预后和确定最佳抗生素治疗至关重要。在某些心内膜炎病例中，诊断过程较为繁琐，尤其是当使用标准培养技术难以检测出致病微生物时。在此，我们报告一例由金氏金杆菌引起的原发性主动脉瓣心内膜炎病例，金氏金杆菌是HACEK菌群中的一种革兰氏阴性菌。此外，我们回顾了1983年至1999年间在我院接受治疗的另外6例由该菌群微生物引起的心内膜炎病例。流行病学研究表明，所有心内膜炎病例中由HACEK菌群微生物引起的不到5%。由于它们在标准培养基上生长缓慢，诊断往往会延迟。我们描述了这类心内膜炎的临床和微生物学特征。
