Llanes R, Sosa J, Guzmán D, Gutiérrez Y, Llop A, Ricardo O
National Reference Laboratory for Neisseria, Tropical Medicine Institute, Pedro Kouri, Havana, Cuba.
Sex Transm Dis. 2001 Feb;28(2):82-3. doi: 10.1097/00007435-200102000-00004.
The Cuban Ministry of Public Health plans to implement the syndromic approach to sexually transmitted diseases in persons with urethral or vaginal syndrome in Cuba using 500 mg ciprofloxacin as therapy. Although the emergence of clinical isolates of Neisseria gonorrhoeae with decreased susceptibility to ciprofloxacin have been sporadically detected in Cuba, there has been no report of isolates that exhibited significant resistance to this drug. This is the first report of the isolation of a N gonorrhoeae strain resistant to ciprofloxacin in Cuba.
Case report.
This case emphasizes the need for awareness regarding the potential emergence of a clinically significant resistance of N gonorrhoeae in Cuba. There is a need for continued antimicrobial susceptibility surveillance of Cuban isolates to ciprofloxacin and other fluoroquinolones.
古巴公共卫生部计划在古巴对患有尿道或阴道综合征的人群采用综合征方法来治疗性传播疾病，使用500毫克环丙沙星作为治疗药物。尽管在古巴已偶尔检测到对环丙沙星敏感性降低的淋病奈瑟菌临床分离株，但尚无对该药物表现出显著耐药性的分离株报告。这是古巴首次报告分离出对环丙沙星耐药的淋病奈瑟菌菌株。
病例报告。
该病例强调了需要意识到古巴淋病奈瑟菌可能出现具有临床意义的耐药性。有必要继续对古巴分离株进行环丙沙星和其他氟喹诺酮类药物的抗菌药敏监测。
