Gorbacheva I A, Kirsanov A I, Orekhova L Iu
Stomatologiia (Mosk). 2001;80(1):26-34.
Generalized periodontitis is a polyetiological disease, pathogenetically bound with internal pathology. The study was made to reveal common somatic mechanisms of generalized periodontitis pathogenesis. The examination of 574 patients has established immunological unbalances, mineral deficiencies and high activity of free radical oxidation of lipids and proteins. The usage of systemic multienzyme remedies, replacement mineral therapy, antioxidants, had correcting effects. This evidences for the presence of close links between pathogenetic mechanisms of generalized periodontitis, functioning according to the mobile's principle.
广泛性牙周炎是一种多病因疾病,在发病机制上与内科疾病相关。本研究旨在揭示广泛性牙周炎发病机制中的常见躯体机制。对574例患者的检查发现了免疫失衡、矿物质缺乏以及脂质和蛋白质自由基氧化活性升高。使用全身多酶疗法、替代矿物质疗法、抗氧化剂具有纠正作用。这证明了广泛性牙周炎发病机制之间存在紧密联系,其按照动态原理发挥作用。