Janion M, Sielski J, Putała J, Bakowski D
Wojewódzki Szpital Zespolony Odddział Kardiologii w Kielcach.
Pol Arch Med Wewn. 2000 Mar-Apr;103(3-4):147-52.
The subject of this trial were 243 patients with uncomplicated acute myocardial infarction, hospitalized in years 1992-1996, who were made an electrocardiographic exercise test in the second or third week of the in-hospital stay and whose further history in the 2-6 period after myocardial infarction (average follow-up time lasted for 4.0 +/- 1.9 years) was known. The aim of this trial was to determine the influence of the positive exercise test on the long-term prognosis after acute myocardial infarction in a group with uncomplicated acute myocardial infarction. The course of infarction and the frequency of cardiac events (cardiac death, reinfarction, revascularisation) occurrence in 78 patients with positive exercise test (group I) were compared with a group of 165 patients with negative exercise test (group II). Both groups were compared in respect to age, gender, history of myocardial infarction, risk factors and the course of the infarction in the in-hospital period. The multivariable logistic regression analyse showed that the positive exercise test did not have a statistically significant influence on the increase of post-hospital morbidity but it correlates with significantly more frequent use of the invasive treatment and reinfarction during the follow-up period in this group. Negative exercise test in patients with uncomplicated acute myocardial was a significant factor of the good long-term prognosis.
该试验的对象为243例无并发症的急性心肌梗死患者,于1992年至1996年住院,他们在住院的第二或第三周进行了心电图运动试验,且已知其心肌梗死后2至6年期间的进一步病史(平均随访时间为4.0±1.9年)。本试验的目的是确定运动试验阳性对无并发症急性心肌梗死患者急性心肌梗死后长期预后的影响。将78例运动试验阳性患者(第一组)的梗死病程及心脏事件(心源性死亡、再梗死、血运重建)发生频率与165例运动试验阴性患者(第二组)进行比较。比较两组患者的年龄、性别、心肌梗死病史、危险因素及住院期间的梗死病程。多变量逻辑回归分析显示,运动试验阳性对出院后发病率的增加无统计学显著影响,但与该组随访期间侵入性治疗的更频繁使用及再梗死显著相关。无并发症急性心肌梗死患者运动试验阴性是长期预后良好的重要因素。