Barros F C, Victora C G, Vaughan J P, Tomasi E, Horta B L, Cesar J A, Menezes M B, Halpern R, Post C L, del Mar Garcia M
PAHO/WHO Latin American Center for Perinatology and Human Development, Montevideo, Uruguay.
Paediatr Perinat Epidemiol. 2001 Jan;15(1):4-11. doi: 10.1046/j.1365-3016.2001.00320.x.
Two studies carried out in 1982 and 1993 in the city of Pelotas, Southern Brazil, provide a unique opportunity for assessing the impact on maternal and child health of the economic and health care changes, which took place in Brazil in this period. The cohorts of mothers and infants of 1982 and 1993 were studied from the time of delivery. In both years, all mothers identified in the city's maternity hospitals answered a standardised questionnaire and their infants were examined. Over 99% of all children born in the city in each of the 2 years were included in the cohorts. Deaths occurring among these children were monitored prospectively, as well as all hospital admissions in the 1993 cohort. In the 1982 study, attempts were made to locate a 25% sample of the children at the mean age of 12 months using the addresses collected at the hospital (82% of the children were located), and all of the cohort children at the mean age of 20 months and 42 months, through a city census (87% were located in both follow-ups). In the 1993 study, 20% of all children plus all low birthweight infants were sought at 12 months of age, using the addresses collected at the hospital, and 95% were successfully traced. There was a 12% fall in the number of births occurring in 1993 (5,304 births), in comparison with 1982 (6,011 births), in spite of the increase in the population of reproductive age in the city during the decade. There was a marked difference in maternal height and weight at the beginning of pregnancy, with women giving birth in 1993 being, on average, 3.4 cm taller and 2.5 kg heavier than those who gave birth in 1982. The proportion of preterm babies (<37 weeks), measured by the date of last menstrual period, increased from 5.6% in 1982 to 7.5% in 1993. The median duration of breast feeding increased from 3.1 months in 1982 to 4.0 months in 1993. At 12 months of age, the prevalence of deficit of weight for age decreased from 5.4% in 1982 to 3.7% in 1993. The prevalence of deficit of height for age, however, increased from 5.3% to 6.1%. The perinatal mortality rate dropped 31%, from 32.2 per 1,000 births in 1982 to 22.1 deaths per 1,000 births in 1993. There was also a marked reduction in the infant mortality rate, from 36.4 per 1,000 livebirths in 1982 to 21.1 per 1,000 livebirths in 1993. The findings of the study indicate that there were improvements in the decade for most of the indicators evaluated, with the exception of birthweight and gestational age. It appears that improvements in perinatal and infant mortality rates are largely due to improvements in the health care sector.
1982年和1993年在巴西南部的佩洛塔斯市开展的两项研究,为评估这一时期巴西经济和医疗保健变革对母婴健康的影响提供了独特契机。对1982年和1993年的母婴队列从分娩时起进行研究。在这两年中,该市妇产医院确定的所有母亲都回答了一份标准化问卷,并且对她们的婴儿进行了检查。这两年中该市出生的所有儿童中有超过99%被纳入队列。对这些儿童中的死亡情况进行前瞻性监测,同时也监测1993年队列中所有住院情况。在1982年的研究中,利用在医院收集的地址试图找到平均年龄为12个月的25%的儿童样本(82%的儿童被找到),并通过城市人口普查找到平均年龄为20个月和42个月的所有队列儿童(两次随访中87%的儿童被找到)。在1993年的研究中,利用在医院收集的地址寻找所有儿童的20%加上所有低体重儿在12个月大时的情况,95%被成功追踪到。与1982年(6,011例出生)相比,1993年的出生数下降了12%(5,304例出生),尽管这十年间该市育龄人口有所增加。怀孕初期母亲的身高和体重有显著差异,1993年分娩的女性平均比1982年分娩的女性高3.4厘米、重2.5千克。根据末次月经日期测量的早产(<37周)比例从1982年的5.6%增至1993年的7.5%。母乳喂养持续时间中位数从1982年的3.1个月增至1993年的4.0个月。在12个月大时,年龄别体重不足患病率从1982年的5.4%降至1993年的3.7%。然而,年龄别身高不足患病率从5.3%增至6.1%。围产期死亡率下降了31%,从1982年每1,000例出生32.2例死亡降至1993年每1,000例出生22.1例死亡。婴儿死亡率也显著降低,从1982年每1,000例活产36.4例降至1993年每1,000例活产21.1例。该研究结果表明,除出生体重和孕周外,这十年中所评估的大多数指标都有所改善。看来围产期和婴儿死亡率的改善很大程度上归因于医疗保健部门的改善。