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Premature discontinuation of clinical trial for reasons not related to efficacy, safety, or feasibility.

作者信息

Lièvre M, Ménard J, Bruckert E, Cogneau J, Delahaye F, Giral P, Leitersdorf E, Luc G, Masana L, Moulin P, Passa P, Pouchain D, Siest G

机构信息

Clinical Pharmacology Unit, Faculté de Médecine Laënnec, BP 8071, 69376 Lyons Cedex 08, France.

出版信息

BMJ. 2001 Mar 10;322(7286):603-5. doi: 10.1136/bmj.322.7286.603.

DOI:10.1136/bmj.322.7286.603
PMID:11238162
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1119794/
Abstract
摘要

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What is the optimal age for starting lipid lowering treatment? A mathematical model.开始降脂治疗的最佳年龄是多少？一个数学模型。
BMJ. 2000 Apr 22;320(7242):1134-40. doi: 10.1136/bmj.320.7242.1134.
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Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study.洛伐他汀对胆固醇水平正常的男性和女性急性冠脉事件的一级预防：空军/德州冠状动脉粥样硬化预防研究（AFCAPS/TexCAPS）的结果
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Early stopping of trials.
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Early closure of European Pimagedine trial. Steering Committee. Safety Committee.
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Statins and coronary heart disease.他汀类药物与冠心病
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Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group.普伐他汀预防高胆固醇血症男性冠心病。苏格兰西部冠心病预防研究组。
N Engl J Med. 1995 Nov 16;333(20):1301-7. doi: 10.1056/NEJM199511163332001.
10
AIDS, ethics, and clinical trials. Institute of Medical Ethics Working Party on the Ethical Implications of AIDS.艾滋病、伦理与临床试验。医学伦理学会艾滋病伦理问题工作小组
BMJ. 1992 Sep 19;305(6855):699-701. doi: 10.1136/bmj.305.6855.699.