Huffman D H, Ferguson R L
Johns Hopkins Med J. 1975 Apr;136(4):183-6.
A patient presented with clinical features of drug overdose. Although heroin was suspected, codeine was identified by drug analysis. The clinical course was complicated by shock, respiratory arrest and laboratory evidence of acute hepatic insufficiency. An inital slow rate of codeine metaboism, possibly related to the hepatic damage, corresponded to prolonged respiratory depression.
一名患者出现药物过量的临床特征。尽管怀疑是海洛因，但药物分析鉴定为可待因。临床过程因休克、呼吸骤停及急性肝功能不全的实验室证据而变得复杂。可待因最初代谢缓慢，可能与肝损伤有关，这与呼吸抑制延长相对应。
