[Diurnal fluctuations of blood lipids and sugar level in healthy persons and in patients with ischemic heart diseases].

Diurnal fluctuations in the level of cholesterol, phospholipids, triglycerides, NEFA and sugar in the blood of practically healthy subjects and in patients with ischemic heart disease, attended by hyperlipoproteinemia of the II and IV types, were studied. Investigations were made at 9 a.m., 3 and 9 p.m. The variations of the lipid fractions and sugar in the blood of practically healthy individuals and of patients with hyperlipoproteinemia showed no essential differences. There were minimal diurnal changes in the cholesterol level, a tendency towards an increase in the level of phospholipids, a statistically significant rise in the content of triglycerides and sugar in the blood and large fluctuations in the level of the NEFA, both upwards and downwards. In patients with hyperlipoproteinemia of the II type variations in the blood cholesterol and phospholipids levels occurring in the course of the day proved to be of the same nature as in the case of normal lipoproteinemia, with no diurnal rise of the sugar level, while the NEFA content showed a distinct upward tendency. In patients it was only the blood cholesterol and triglycerides level that remained at a statistically significant higher level throughout the day.