Smirnov I P
Kardiologiia. 1975 Feb;15(2):89-95.
Evidence has been obtained that in patients with mitral defects of the heart and circulatory insufficiency at rest there is observed total and alveolar hyperventilation accompanied by a falling efficiency of the alveolar ventilation. In patients with mitral stenosis there is noted a progressive deterioration of the oxygen diffusion in the lungs, which depends upon the stage of the circulatory insufficiency. In patients where incompetence of the mitral valve prevails the diffusion disorders become manifest only in cases of a sharply pronounced circulatory insufficiency.
有证据表明,患有心脏二尖瓣缺损且静息时存在循环功能不全的患者,会出现全肺和肺泡过度通气,同时伴有肺泡通气效率下降。二尖瓣狭窄患者肺部的氧扩散功能会逐渐恶化,这取决于循环功能不全的阶段。二尖瓣关闭不全为主的患者,仅在循环功能不全明显加剧的情况下才会出现扩散障碍。