Sch0nheyder H C, Maunsbach A B
Kidney Int. 1975 Mar;7(3):145-53. doi: 10.1038/ki.1975.22.
The transition between the glomerulus and the proximal tubule was studied by light and electron microscopy in perfusion-fixed rabbit kidneys. In most nephrons a transitional segment of tubule occurred between the Bowman's capsule and the proximal tubule proper. This initial part of the tubule was lined by flattened cells and formed a cytologically distinct neck segment. The nephron population was heterogeneous with respect to the length of this neck segment regardless of the level of the cortex. The neck cells contained an abundance of thin filaments often oriented at right angles to the long axis of the tubule and comparable in thickness to actin filaments. The presence of actin-like filaments suggests that neck cells may effect changes in the diameter of the neck segment and, thus, influence single nephron glomerular filtration rate.
利用光镜和电镜对灌注固定的兔肾中肾小球与近端小管之间的过渡区域进行了研究。在大多数肾单位中，在鲍曼囊和近端小管本身之间出现了一段过渡性的小管。小管的起始部分由扁平细胞构成，形成了一个细胞学上独特的颈部段。无论皮质的水平如何，该颈部段的长度在肾单位群体中是异质的。颈部细胞含有大量细肌丝，这些细肌丝通常与小管的长轴成直角排列，其厚度与肌动蛋白丝相当。肌动蛋白样丝的存在表明颈部细胞可能会影响颈部段的直径变化，从而影响单个肾单位的肾小球滤过率。
